Ketoconazole: cov lus qhia rau kev siv thiab tshuaj xyuas
Lub npe Latin: Ketoconazole
ATX Code: J02AB02 (ntsiav tshuaj thiab tsiav tshuaj), D01AC08 (lee), G01AF11 (thaj chaw muaj tshuaj)
Tus nquag ua haujlwm: Ketoconazole (Ketoconazole)
Cov tsim tawm: VERTEX, AO (Russia), Pharmaprim (Republic of Moldova), CJSC Lekhim-Kharkov (Ukraine)
Qhia kho cov lus piav qhia thiab yees duab: 11.26.2018
Cov nqi hauv khw muag tshuaj: los ntawm 137 rubles.
Ketoconazole yog cov tshuaj tua kabmob.
Tso tawm daim ntawv thiab muaj pes tsawg leeg
- ntsiav tshuaj: yuav luag dawb lossis dawb nrog ib qho chamfer (10 pcs. hauv lub hlwv, hauv pob ntawv qhwv ntawm 1 lossis 3 hlwv),
- tsiav tshuaj (10 pcs. nyob rau hauv ib lub thoob blister, nyob rau hauv cardboard pob 2 blisters),
- lub paum ntawm qhov chaw mos: dawb los yog dawb nrog lub daj zas, qhov khoob hauv lub ntsej muag nrog lub ntsej muag kawg, tej zaum yuav muaj lub suab hais tawm lossis lub pas nrig cua rau ib ntu (5 pcs. hauv ib lub hlwv, hauv pob ntawv qhwv ntawm 1 lossis 2 lub hlwv),
- cream rau kev siv sab nraud 2%: homogeneous loj ntawm cov xim dawb los yog dawb nrog lub daj tinge ntawm cov xim (10 g lossis 15 g txhua qhov hauv cov leeg txhuas, hauv daim duab los qhwv 1 lub raj),
- tshuaj zawv plaub hau (150 ml hauv ib lam fwj, hauv ib daim ntawv qhwv ib pob 1 fwj).
1 ntsiav tshuaj muaj:
- cov tshuaj nquag: ketoconazole - 0.2 g,
- Cov khoom siv pabcuam: lactose, pob kws hmoov txhuv nplej siab, qis molecular phaus polyvinylpyrrolidone, colloidal silicon dioxide, magnesium stearate.
Hauv 1 lub tshuaj ntsiav, lub ntsiab lus ntawm cov tshuaj nquag - ketoconazole, yog 0.2 g.
1 lub suppository muaj:
- cov tshuaj nquag: ketoconazole - 0.4 g,
- Cov khoom siv pabcuam: butylhydroxyanisole, glycerides ib nrab hluavtaws (Suppocir-AM).
1 g ntawm cream muaj:
- cov tshuaj nquag: ketoconazole - 0.02 g,
- Cov khoom siv pabcuam: kua paraffin, emulsir 61 WL 2659, nipagin, labrafil M 2130 CS, cov dej huv.
Muaj tsuaj zawv plaub hau:
- cov tshuaj nquag: ketoconazole - 2%,
- Cov khoom siv pabcuam: sodium laureth sulfate, cocmidopropyl betaine, sodium lauryl ethoxysulfosuccinate, cocoglucoside glyceryl oleate, polyquaternium-7, cocamide MEA, PEG (polyethylene glycol) -7 glyceryl cocoate, triethanolamine, laureth-3, sodium chloride, sodium chloride, dialyyl-3 muaj pes tsawg leeg naj hoom.
Cov Tshuaj Hauv Tshuaj
Ketoconazole yog ib qho hluavtaws sib txuas ntawm imidazole, ib cov tshuaj tua kabmob nrog cov kab mob ua haujlwm ntau thiab fungistatic. Qhov ua haujlwm ntawm mycostatic ntawm cov khoom nquag yog vim nws lub peev xwm los inhibit qhov synthesis ntawm ergosterol, phospholipids thiab triglycerides. Qhov no ua rau muaj kev hloov pauv ntawm lipid muaj pes tsawg leeg ntawm daim nyias nyias ntawm cov hu ua fungi thiab kev ua txhaum ntawm permeability ntawm phab ntsa.
Cov kab mob me me hauv qab no yog nkag siab rau ketoconazole: dermatophytes [Trichophyton tshwj xeeb (spp.), Microsporum spp., Epidermophyton floccosum], poov xab thiab poov xab-zoo li fungi (Pityrosporum spp., Candida spp., Torulopsis, Cryptococcus spp.) , Streptococcus spp.), Cov tshuaj hu ua Dimorphic fungi thiab eumycetes.
Cov Tshuaj Pharmacokinetics
Tom qab qhov ncauj tswj hwm, ketoconazole yog qhov zoo nqus. Lub sij hawm mus cuag cov siab tshaj plaws ntshav siab yog 1-2 teev.
Kev khi rau cov ntshav plasma protein - 99%.
Thawj Theem T1/2 (ib nrab-lub neej) yog 2 teev, theem ob yog 8 teev.
Nyob rau hauv 96 teev, nws yog tas li tsis muaj zog metabolites thiab tsis hloov li 70% ntawm qhov koob tshuaj noj. Los ntawm cov hnyuv - 57%, dhau los ntawm lub raum - 13%.
Kev nqus ntawm lub cev nrog kev siv sab nraud lossis sab hauv intravaginal yog qhov tsis zoo.
Tshuaj thiab tsiav tshuaj
Kev siv tshuaj ntsiav thiab ntsiav tshuaj Ketoconazole yog qhia rau kev kho thiab tiv thaiv mycoses los ntawm microorganisms rhiab rau cov tshuaj:
- kev kis mob ntawm cov qog ua kua ntawm txoj hnyuv,
- cov qhov txhab mob tawv nqaij heev, plaub hau thiab rau tes (suav nrog dermatophytosis, onychomycosis, lichen ntau xim),
- mauj tshuaj mycoses: blastomycosis, candidiasis, histoplasmosis, paracoccidiomycosis, coccidiomycosis,
- mob kheesxaws hauv chaw mos ua mob candidiasis, nrog kev tsis muaj txiaj ntsig ntawm kev kho hauv zos,
- fungal kis kab mob hauv cov neeg mob debilitated, suav nrog kev tiv thaiv kab mob (rau kev tiv thaiv).
Cream rau kev siv sab nraud 2%
Kev siv sab nraud ntawm Ketoconazole cream yog qhia kev kho mob ntawm daim tawv nqaij mycoses tshwm sim los ntawm cov nceb nkag siab ketoconazole:
- daim tawv nqaij candidiasis
- mob ncauj plab epidermophytosis,
- Daim tawv nqaij du (duav),
- epidermophytosis ntawm tus taw thiab tes,
- seborrheic dermatitis los ntawm Pityrosporum ovale,
- pityriasis versicolor.
Kev siv ketoconazole zawv plaub hau yog qhia rau kev kho mob thiab tiv thaiv kev loj hlob ntawm lub cev muaj roj ntawm lub hau, suav nrog pityriasis versicolor thiab dandruff.
Cov Yuav Tsum Muaj
- mob siab ua rau daim siab,
- concomitant txoj kev kho nrog terfenadine, astemizole, triazolam, cisapride, quinidine, simvastatin, lovastatin, pimozide,
- pub niam mis
- ua kom lub cev tsis haum rau cov tshuaj ntawm cov tshuaj.
Raws li cov lus qhia, Ketoconazole yuav tsum tau ua nrog ceev faj thaum muaj kab mob siab, muaj keeb kwm kev phiv tshuaj rau cov tshuaj, mob ua rau lub qog ua ke, nrog rau cov tshuaj tiv thaiv kab mob, yog tias tsim nyog, siv tshuaj ntev los kho hepatotoxic.
Kev siv cov ketoconazole ntsiav tshuaj thaum cev xeeb tub tsuas yog ua tau tsuas yog tshwj xeeb, thaum kev cia siab ua rau leej niam muaj peev xwm tshaj qhov ua teeb meem rau tus me nyuam hauv plab.
- mob siab ua rau daim siab,
- pub niam mis
- ua kom lub cev tsis haum rau macrolides thiab lwm yam tshuaj ntawm cov tshuaj.
Thaum lub sijhawm cev xeeb tub, kev siv cov tshuaj ntsiav yog tso cai tsuas yog thaum muaj kev cia siab rau kev kho mob rau leej niam ntau tshaj qhov ua rau muaj kev phom sij rau cov menyuam hauv plab.
Cov tshuaj zawv plaub hau nrog Ketoconazole
Ketoconazole - Cov tshuaj tiv thaiv kev ua kom tawv nqaij uas tiv thaiv kom tsis txhob pom khaus tawv nqaij thiab pab kom lub cev ntaj zoo. Nws muaj nyob hauv tshuaj pleev, gels, tshuaj zawv plaub hau.
Hauv cov tshuaj zawv plaub hau uas muaj tib lub npe, cov tshuaj ua kom muaj ntsiab lus yog 2%. Cov nyiaj muaj cov nram qab no cov txiaj ntsig:
- zoo tshem tawm cov dandruff,
- tib lub sijhawm daws cov teeb meem ntawm plaub hau poob,
- thoob cov txee ntawm tus nqi tsawg muag hauv khw muag tshuaj network,
- yooj yim mus siv,
- Nws yog ua ke nrog ntau yam kev kho mob dandruff.
Yog tias peb tham txog qhov tsis raug, nws tsuas yog ib qho. Zoo li ib yam tshuaj pleev ib ce khoom, ketoconazole tej zaum yuav ua rau muaj kev fab tshuaj.
Feem ntau, cov tshuaj ketoconazole muaj nyob hauv ntau yam tshuaj zawv plaub hau los tua ntshauv:
- MycozoralCov. Cov tshuaj nquag tshem tawm ntawm tev tawm, khaus thiab lwm yam cim ntawm dandruff. Thov nws peb zaug ib lim tiam rau ib hlis. Cov tshuaj muaj tus nqi tsim nyog,
- Keto Dandruff Zawv Zuaj NtxivCov. Kuj yog hom tshuaj tshiab, uas tseem muaj zinc pyrithione. Cov tshuaj tshem tawm cov tsos mob thiab ua rau dandruff. Cov txheej txheem kho yog siv cov tsuaj zawv plaub hau ob zaug ib lim tiam rau ib hlis,
- Ketokenazole Zn2 +Cov. Nws thaiv qhov rov tsim tawm ntawm cov fungus. Lub sijhawm kho thiab qhov siv ntau npaum li cas tau txiav txim siab ntawm tus kheej,
- SebozolCov. Nws txawv ntawm analogues nyob rau hauv uas nws txoj kev siv raug tso cai rau cov menyuam yaus txog 1 xyoos thiab cov poj niam cev xeeb tub. Siv cov khoom ob zaug ib lim tiam,
- NizbCov. Cov npe no tau hnov los ntawm ntau. Lub caij no, nws cov khoom siv tuaj yeem ua rau ua xua.
Nyeem cov lus qhia yuav ua li cas xaiv cov tshuaj zawv plaub hau kom haum rau tus txiv neej lossis tus poj niam, nrog rau ziab lossis ziab qhuav.
Sab sij huam
- los ntawm lub plab zom mov: tsis tshua muaj - xeev siab, ntuav, tsis tshua muaj heev - muaj kev hloov pauv hauv daim siab hloov pauv, kab mob siab,
- los ntawm cov hlab ntsha hauv lub cev: tsis tshua muaj - mob taub hau, kiv taub hau, photophobia, thim rov qab nce siab ntxiv ntawm kev mob siab intracranial, paresthesia,
- los ntawm kev yug me nyuam: tsis tshua muaj (tiv thaiv keeb kwm yav dhau los siv lub sijhawm ntev) - kev coj khaub ncaws tsis xwm yeem, kev txwv tsis pub androgen tsim, oligospermia, gynecomastia,
- los ntawm cov kab mob hematopoietic: tsis tshua muaj - thrombocytopenia.
- muaj peev xwm ua tau: raws plab, xeev siab, ntuav, kab mob pob txha, mob taub hau, ntxhov ntxhov pw tsaug zog, tsis vwm dab tsi, photophobia, thrombocytopenia, exanthema,
- tsis tshua muaj mob: ua npaws, plaub hau poob, kev ua xua (urticaria, pob khaus tawv nqaij), gynecomastia, oligospermia, txo qis libido, mob caj dab,
- hauv cov menyuam yaus hauv qee qhov mob tsawg: kev poob siab, ntxhov siab, pw tsis tsaug zog, hyperkinesia, mob pob txha ntsej muag tuaj yeem tshwm sim.
Cov lus qhia tshwj xeeb
Yog tias cov tsos mob ntawm qhov tshwm sim tsis zoo, kev siv tshuaj yuav tsum tsis ua ntxiv thiab sab laj nrog koj tus kws kho mob.
Yog hais tias lub sijhawm ntawm kev noj cov ntsiav tshuaj ntau dua 14 hnub, kev kho yuav tsum nrog kev soj ntsuam ib txwm muaj ntawm daim duab ntawm ntu ntshav thiab mob siab ua haujlwm.
Yog tias siv kev sib tw ua kom tiav ib qho yog tsim nyog, Ketoconazole ntsiav tshuaj yuav tsum tau noj 2 xuaj moos ua ntej npaj tshuaj antacid.
Thaum noj ketoconazole sab hauv, kev haus dej cawv ntawm lub cev yog contraindicated.
Tawm tsam keeb kwm yav dhau los ntawm kev siv cov tshuaj tiv thaiv nyob rau hauv ib tus khub sib deev, hauv qee kis, hyperemia ntawm chaw mos yuav tshwm sim.
Nrog kev kho mob rau lub paum, qhov kev kho mob tib si ntawm ob leeg deev yog qhov pom zoo, qhov no yuav txo qhov kev pheej hmoo ntawm tus mob ntxiv.
Cov tshuaj txhawb nqa tuaj yeem txo txoj kev cia siab ntawm cov txheej txheem tiv thaiv kev txwv tsis pub muaj menyuam yaus xws li hnab looj thiab cov hnab looj qau ua paum.
Cov tshuaj nplaum tuaj yeem siv sab nrauv nkaus xwb, nws tsis tuaj yeem siv rau hauv kev xyaum ophthalmic. Tsis txhob cia cov tshuaj nplaum mus rau hauv koj lub qhov muag.
Yog tias kev siv cov tshuaj nplaum yog tom qab siv sijhawm ntev los ntawm kev siv sab hauv glucocorticosteroids, tawv nqaij yuav tshwm sim. Txhawm rau tshem tawm nws, nws raug nquahu kom txuas ntxiv glucocorticosteroid tswj hwm thaum sawv ntxov rau 14-21 hnub, thiab ketoconazole thaum yav tsaus ntuj. Tom qab ntawd cov koob tshuaj glucocorticosteroid yuav tsum maj mam txo kom txog thaum txo tag nrho. Yog tias ib qho kev ua haujlwm glucocorticosteroid muaj zog heev thaum xub thawj siv, nws tuaj yeem hloov los ntawm kev muaj zog dua.
Kev cuam tshuam rau kev muaj peev xwm tsav tsheb thiab cov txheej txheem nyuaj
Noj cov ntsiav tshuaj thiab tshuaj ntsiav tuaj yeem ua rau muaj kev mob tshwm sim hauv tus neeg mob uas cuam tshuam qhov ceev ntawm lub cev kev xav thiab lub siab ntawm kev saib xyuas, yog li ceev faj yuav tsum siv thaum ua haujlwm uas muaj kev phom sij, suav nrog thaum tsav tsheb.
Kev siv cov tshuaj tiv thaiv thiab cov tshuaj nplaum tsis cuam tshuam rau tus neeg mob lub peev xwm los tsav tsheb thiab cov txheej txheem nyuaj.
Cev xeeb tub thiab lactation
Kev siv cov ntsiav tshuaj thiab cov tshuaj ntsiav thaum cev xeeb tub tsuas yog ua tau tsuas yog tshwj xeeb thaum kev cia siab rau kev kho mob rau leej niam ntau tshaj qhov ua rau muaj kev phom sij rau cov menyuam hauv plab.
Kev siv cov ntsiav tshuaj thiab cov tshuaj ntsiav thaum lactation yog contraindicated. Yog tias nws yuav tsum tau noj ketoconazole sab hauv, kev pub mis niam yuav tsum tsis ua mus ntxiv.
Tshuaj ntawm cov tshuaj suppositories yog contraindicated hauv thawj peb lub hlis thaum cev xeeb tub. Kev siv cov tshuaj tiv thaiv nyob rau xyoo II thiab III ntawm kev xeeb tub thiab kev pub niam mis yog ua tau yog tias, raws li kws kho mob, cov txiaj ntsig xav tau ntawm kev kho rau leej niam tshaj qhov kev pheej hmoo tam sim no rau tus me nyuam thiab tus menyuam.
Nws yog qhov ua tau los siv cov tshuaj pleev thaum lub cev xeeb tub thiab lactation vim qhov qis qes ntawm kev nqus ntawm ketoconazole mus rau hauv cov kab ke ua haujlwm.
Siv rau thaum yau
Pom zoo ntau npaum rau cov ntsiav tshuaj thiab tsiav tshuaj:
- dermatomycoses, ntau-xim lichen, candidiasis ntawm daim tawv nqaij thiab qhov ncauj kab noj hniav, onychomycosis, cov kab mob mycoses: cov menyuam yaus hnyav dua 30 kg - 1 pc. (200 mg) ib hnub ib zaug, yog tias tsim nyog, cov koob tshuaj tuaj yeem raug nce rau 2 pcs. Cov menyuam yaus lub cev nyhav txog 15-30 kg - 1/2 pcs. (100 mg) 1 zaug nyob rau ib hnub. Lub sijhawm kho: dermatomycosis - txog 28 hnub, muaj xim lichen - 10 hnub, candidiasis ntawm daim tawv nqaij thiab lub qhov ncauj tawm - 14-21 hnub, onychomycosis - txog thaum kho thiab mycological txhim kho los ntawm 180 mus rau 360 hnub, mentsis tshuaj rau lub cev - 30-60 hnub,
- kev tiv thaiv cov kab mob fungal: raws li 4-8 mg rau 1 kg ntawm tus menyuam qhov hnyav ib hnub. Lub sijhawm ua haujlwm ntawm cov chav kawm yog kho raws tus kheej.
Txoj kev paum ntawm qhov chaw mos: tsis muaj xov xwm hais txog kev nyab xeeb thiab kev ua haujlwm ntawm lawv kev siv hauv cov menyuam ntxhais hnub nyoog qis dua 12 xyoos, yog li ntawd kev siv yog contraindicated.
Nrog kev ceev faj, nws raug nquahu kom siv tswm ciab uas muaj hnub nyoog 12-18 xyoo.
Yeeb tshuaj sib cuam tshuam
Nrog tib lub sijhawm siv ketoconazole nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab tsiav tshuaj:
- terfenadine, astemizole, triazolam, cisapride, quinidine, simvastatin, lovastatin, pimozide: tshuaj uas lawv sib xyaw nrog ketoconazole yog contraindicated,
- antacids, anticholinergics, H2-blockers: pab txhawb kom txo qis ntawm ketoconazole,
- rifampicin, isoniazid, rifabutin, carbamazepine, phenytoin: ua rau kom cov tshuaj hauv ntshav plam tsawg dua,
- cyclosporine, anticoagulants indirect, indinavir, saquinavir, disulfan, vincristine, docetaxel, nifedipine, digoxin, verapamil, carbamazepine, alfentanil, sildenafil, buspirone, alprazolam, midazolam, ntshav muaj feem ntawm trifabimin.
Nrog kev siv intravaginal thiab sab nraud ntawm ketoconazole, muaj lub suab tsis muaj kev nqus ntawm cov khoom, yog li ntawd kev cuam tshuam ntawm cov tshuaj tiv thaiv kev noj tshuaj thiab qab zib nrog lwm cov tshuaj tsis zoo li.
Cov qauv ntawm Ketoconazole yog: ntsiav tshuaj - Ketoconazole DS, Fungavis, Funginok, Oronazole, Fungistab, Mikozoral, Nevirapine, Ritonavir, Inviraza, Ketazol, tsiav tshuaj - Pradax, Crixivan, lee - Dermazole, Nizoral, Ketozoralit, Maze, oint - Ketoconazole-Altpharm, Livarol, Ketodyne, tsuaj zawv plaub hau - Mikanisal, Nizoral, Perhotal, Nezo-Ua liaj ua teb.
Dab tsi yog qhov muaj txiaj ntsig hauv kev kho tus txiv neej txawv mas?
Cov kev tshawb fawb txog kev siv ketoconazole-based zawv plaub hau hauv kev kho androgenetic alopecia Ketoconazole Zawv plaub hau: Cov nyhuv ntawm Kev Siv Ntev hauv Androgenic Alopecia pom tias muaj kev nce hauv plaub hau thiab cov plaub hau loj hauv cov theem anagen zoo li minoxidil 2%. Hauv lwm lo lus, ketoconazole zawv plaub hau tuaj yeem ua kom zoo li minoxidil. Txoj kev tshawb no koom nrog 39 tus txiv neej nrog rau qhov thib peb qib ntawm kev do hau raws li Norwood, uas tsis muaj dandruff lossis tawv nqaij tawv. Los ntawm rau lub hlis, plaub hau tuab tau nce mus rau 296 ib cm2, uas yog + 18% hauv cov neeg mob uas siv tshuaj zawv plaub hau nrog ketoconazole (Nizoral tsuaj zawv plaub hau ob mus rau plaub zaug hauv ib lub lis piam) thiab nce txog 306 ib cm2 + 11% hauv cov neeg mob uas siv minoxidil 2% thiab tsuaj zawv plaub hau tas li Cov. Kuj tseem muaj qhov nce ntawm qhov taub ntawm cov plaub hau txuas ntxiv li 7% hauv ob pawg.
Ketoconazole ua haujlwm li cas?
Ketoconalosis inhibits ergosterol hluavtaws ntawm cov kab mob fungal thiab lub cev tsis haum ntawm phab ntsa permeability. Txhawb nqa cov dermatophytes, cov poov xab hu ua fungi, dimorphic fungi, emumycetes, staphylococci thiab streptococci. Tej zaum, tsis tsuas yog androgens (dihydrotestosterone), tab sis kuj muaj cov txheej txheem ua si lub luag haujlwm tseem ceeb hauv cov txheej txheem ntawm miniaturization ntawm cov hauv paus plaub hau hauv androgenetic alopecia. Ketoconazole muaj qee cov nyhuv los tiv thaiv. Cov no yog tag nrho cov kev xav, qhov tiag tiag mechanism ntawm cov nyhuv ntawm ketoconazole ntawm qhov ntom thiab txoj kab uas hla ntawm cov plaub hau tsis tuaj yeem nkag siab.
Yuav siv cov tshuaj twg?
Cov no yog Nizoral, Vitoral, Orazol, Ketozoral thiab lwm yam tshuaj zawv plaub hau uas muaj 2% ketoconazole. Cov tshuaj no tuaj yeem yuav hauv txhua lub tsev muag tshuaj. Lub Nizoral qub feem ntau raug nqi ntau zaug ntxiv. Rau kev sib piv, Nizoral nyob rau hauv Ukraine raug nqi 200 hryvnias (yim las) piv rau 80 hryvnias (peb duas las) rau Ketozoral.
Yuav siv cov tshuaj zawv plaub hau li cas?
Nrog koj tus kws kho mob tham ua ntej. Yuav cov zawv plaub hau nrog ketoconazole 2%.Yaug koj lub taub hau nrog dej sov, siv tshuaj zawv plaub hau, zaws koj cov tawv taub hau, tos peb mus rau tsib feeb, yaug tawm cov tsuaj zawv plaub hau. Rov ua 2 rau 3 zaug ib lub lim tiam kom tau txais txiaj ntsig zoo. Thov nco ntsoov tias koj tsis tuaj yeem siv tshuaj zawv plaub hau yog tias koj lub taub hau tau ntub ntev tshaj kaum feeb ua ntej. Qhov tseeb yog tias tom qab lub sijhawm no hauv chav dej, lub permeability ntawm daim tawv nqaij poob qis.
Yuav ua li cas xaiv cov tsuaj zawv plaub hau?
Nws yog ib qho tsim nyog kom ze rau kev xaiv cov zawv plaub hau ib tus zuj zus. Kev siv tshuaj tiv thaiv kab mob tawv tawv uas tau pab ib tus neeg tuaj yeem tsis muaj nqis rau lwm tus.
Cov lus qhia yog txuas rau txhua cov tshuaj, qhov twg qhov ntsuas pom kev siv, lub hauv paus ntsiab lus ntawm tsuaj zawv plaub hau, thiab zoo li ua tau contraindications tau ntxaws. Nyob rau hauv kom tsis txhob yuam kev, koj yuav tsum ua raws li cov lus sau tseg.
Yuav siv li cas?
Dermatologist thiab trichologist pom zoo kom siv cov Ketoconazole rau cov tawv nqaij mob tawv nqaij, tawv nqaij, thiab lwm yam kab mob ntawm daim tawv nqaij ntawm lub taub hau. Siv nws cov hauv qab no:
- Thov zawv plaub hau me ntsis kom ntub cov plaub hau thiab ua npuas dej.
- Rub mus rau ntawm daim tawv nqaij nrog kev zaws cov ntawv thov ib ncig.
- Cov tshuaj yeeb dej caw ntawm tus neeg sawv cev yuav tsum ua rau 5 feeb.
- Tom qab lub sijhawm no, yaug tawm cov tshuaj nrog dej sov ntau.
Txhawm rau txuag nyiaj, tsis ntev ua ntej siv, koj tuaj yeem ntxuav koj cov plaub hau nrog zawv plaub hau zoo tib yam.
Hauv kev tawm tsam kom ntov, qhov zoo tshuaj no tuaj yeem siv rau ib hlis raws li cov txheej txheem 1 zaug hauv 3 hnubCov. Ntxiv mus, nws tuaj yeem siv los ua ib txoj hauv kev tiv thaiv: 1 lub sijhawm hauv 2 lub lis piam.
Tus kho zoo ntawm zawv plaub hau
Ketoconazole, ntawm lub hauv paus uas tsim cov zawv plaub hau, yog ib qho kev tso tawm ntawm imidazoldioxolan. Thaum ua ntawv thov rau thaj chaw muaj teeb meem, cov tshuaj hloov cov lipid muaj pes tsawg leeg ntawm daim nyias nyias thiab ua rau kev puas tsuaj ntawm phab ntsa cell ntawm cov poov xab thiab dermatophytes, uas ua rau muaj kev kub ntxhov thiab lwm yam kab mob fungal. Kev siv cov tsuaj zawv plaub hau ua rau maj mam ploj mus ntawm cov nplai dawb hauv plaub hau, tshem tawm qhov khaus thiab tawv nqaij ntawm tawv taub hau.
Kev kho kiag
Cov neeg mob uas xav kom tshem tawm ntawm dandruff, seborrheic dermatitis lossis ua rau tawv taub hau yog pom zoo kom ntxuav lawv cov plaub hau nrog tsuaj zawv plaub hau ob zaug hauv ib lub lis piam rau 3-4 lub lim tiam. Nrog rau pityriasis versicolor, cov tshuaj yuav tsum tau siv ib hnub ib hnub. Lub sijhawm kho ntawm qhov no yog 5 hnub.
Cov neeg mob uas xav tau tshem ntawm seborrheic dermatitis raug pom zoo kom ntxuav lawv cov plaub hau nrog zawv ob zaug ib zaug rau 3-4 lub lim tiam.
Cov nqe lus ntawm kev muag khoom thiab chaw cia khoom
Ketoconazole tau muag hauv khw muag tshuaj. Daim ntawv qhia rau nws txoj kev yuav khoom yog tsis xav tau.
Tsuaj zawv plaub hau yuav tsum muaj kev tiv thaiv los ntawm noo noo thiab ncaj qha tshav ntuj. Nws raug nquahu kom nws nyob hauv qhov ntsuas cua ntawm +18 ... + 25 ° C nyob rau hauv qhov chaw sab nraum qhov chaw zoo ntawm menyuam yaus. Lub txee lub neej ntawm cov neeg ua hauj lwm kho tau tsuas yog 3 xyoos txij li hnub ntawm kev tsim khoom.
Kev piav qhia thiab siv
Cov plhaws muaj tsuaj zawv plaub hau nrog ketoconazole muaj nyob hauv cov hwj roj hmab yas, xim pob tshab. Lub thawv ntawv thawv muaj cov khoom siv uas suav nrog ib fwj tshuaj zawv plaub hau, ib qho kev qhia rau kev siv (tsis tas li, qee zaus cov ntaub ntawv qhia nyob rau ntawm lub thawv). Muaj nyob rau hauv ntau thiab tsawg ntawm 20 thiab 60 ml. Tsuaj zawv plaub hau muaj cov nram qab no:
- Pob tshab:
- Nruab nrab ntom
- Liab muag txiv kab ntxwv
- Tshaj tawm cov lus tsis hnov tsw.
Thaum siv cov tshuaj zawv plaub hau pleev cov plaub hau, nws ua npuas ncauj zoo. Nquag, nws tsis ua rau tsis xis nyob.
Cov Khoom Piav Qhia: Nees Zog, Elf, Sulsen, Mirolla, Zinc pyrithione
Antifungal tsuaj zawv plaub hau rau cov neeg muaj tawv. Kev mob siab rau kho qhov dandruff, ua yeeb yam ntawm microflora pathogenic thiab nres nws txoj kev loj hlob. Lub Cheebtsam pabcuam daws cov kev voos thiab khaus uas nrog seborrhea, dermatitis, lichen.
Txij li cov tshuaj yog npaj tshwj xeeb rau kev siv sab nraud, cov ntaub ntawv ntawm kev zom zaub mov thiab nws raug tshem tawm ntawm lub cev tsis tuaj. Cov tshuaj zawv plaub hau uas muaj ketoconazole tshwj xeeb tshaj yog ua tawm tsam cov kab mob ntawm hom Epidermophyton, Microsporum, Trichophyton, Candina, thiab lwm yam.
Cov Lus Pom Zoo Zawv Plaub Hau
Txawm hais tias ketoconazole yog cov tshuaj zawv plaub hau uas tsis kho, ib tus kws kho mob yuav tsum sau nws rau qee yam cim. Ua ntej sau ntawv kho txoj kev kho mob, kws kho mob lossis kws tshaj lij feem ntau ua ib qho kev tshawb fawb los txiav txim siab txog hom fungus, vim tias tsis yog txhua cov tshuaj muaj txiaj ntsig zoo ib yam rau txhua tus kab mob. Cov tsuaj zawv plaub hau no tam sim no siv los kho mob candidiasis thiab dermatophytosis, qee zaum lwm tus neeg.
Ua ntej siv thawj zaug, sim rau tus kheej rhiab heev rau cov khoom siv. Yog tias koj xaj zawv plaub hau koj tus kheej, tsis muaj kws kho mob sau ntawv, nws zoo dua rau sab laj nrog nws ua ntej siv thawj zaug.
Cov lus qhia rau kev siv
Cov lus qhia txog kev siv Ketoconazole zawv plaub hau hais tias nws yuav tsum tau siv ntawm ntau ncua sij hawm hauv txhua kis, muaj cov kab mob tshwj xeeb. Nws yog tshuaj rau siv tsis pub ntau tshaj 1 zaug hauv 5 hnub thiab tsis pub tsawg tshaj 1 zaug hauv ob lub lis piam. Kev siv ntau zaus yuav txawv nyob hauv chav kawm. Nws siv raws li cov zawv plaub hau ib txwm.
- Thov kom txaus tsim nyog rau cov plaub hau ntub dej.
- Ua npuas ncauj kom huv si, kis tusyees hla lub hau,
- Tso rau 5 mus rau 10 feeb los yog yaug tawm sai li sai tau yog muaj qhov tsis xis nyob,
- Yaug koj cov plaub hau nrog dej sov kom ntau.
Nquag, cov kev xav tsis zoo yuav tsum tsis txhob tshwm sim thaum tawm hauv tsuaj zawv plaub hau ntawm curls.
Leej twg thiaj tsis haum?
Txog ketoconazole ntau dua li kev soj ntsuam zoo txaus, nws twb tau pab ntau tus neeg los daws cov teeb meem tsis zoo li khaus.
Cov zawv plaub hau yuav tsis ua haujlwm yog tias:
- kuaj tsis ncaj ncees lawm
- muaj ib tug neeg intolerance Cheebtsam ntawm cov tshuaj.
Kev siv cov tsuaj zawv plaub hau nrog cov ntsiab lus qis dua ntawm cov tshuaj ketoconazole nquag tuaj yeem txo cov kev mob tshwm sim. Yog tias qhov no tsis pab, koj yuav tsum tam sim ntawd tso tseg txoj kev siv ntawm cov tshuaj.
Yuav kom lub ntsiab
Txoj kev ua haujlwm zoo thaum siv zawv plaub hau yog pom tom qab 4-5 lub lis piam los ntawm kev pib siv. Ua tsaug rau cov tshuaj yeeb dej caw, cov tshuaj no zoo heev tsis tsuas yog ua rau dandruff, tab sis kuj tseem nyob rau theem pib ntawm kev do hau.
Nws yog ib qho tsim nyog los tua dandruff. Lub sijhawm sai dua koj to taub qhov teeb meem thiab ua cov kauj ruam los daws nws, ntau dua qhov muaj feem ntawm cov plaub hau rov qab.
Kev ntsuas rau siv
Ketoconazole yog npaj rau kev kho ntawm pob zeb tsis meej pem thiab cov kab ke.
Hauv daim ntawv ntawm cov ntsiav tshuaj, nws yog siv rau cov kabmob hauv qab no:
- Cov kab mob Folliculitis, dermatomycosis thiab onychomycosis tshwm sim los ntawm blastomycetes (suav nrog epidermophytosis ntawm tes thiab taw, tawv nqaij ntawm tus mob tawv nqaij, ua kom tawv nqaij tawv nqaij zoo nkauj, dermatomyc los ntawm Pityrosporum ovale, mob pob txha nqaj qog, mob ntshav qab zib, mob ntshav qab zib ua kom mob).
- Blastomycetosis ntawm lub qhov ncauj ntawm lub plab, lub plab hnyuv, ua kom lub plab hnyuv siab raum thiab lwm yam mycoses ntawm cov nruab nrog sab hauv.
Sab hauv, cov tshuaj tseem coj los ua kev tiv thaiv kab mob los tiv thaiv kev txhim kho cov kab mob fungal hauv cov neeg mob uas txo cov tshuaj tiv thaiv kab mob.
Kev ntsuas rau kev siv zawv plaub hau:
- Mycosis ntawm lub hau,
- Cov plhaws
- Pwm kev mob pwm,
- Seborrheic dermatitis,
- Pityriasis versicolor.
Hauv daim ntawv ntawm lub paum ntawm lub paum, ketoconazole yog tus kws kho mob hauv qab no:
- Kev kho mob ntawm kev rov muaj dua thiab mob qhov chaw mos ntawm qhov chaw mos,
- Kev tiv thaiv kab mob fungal paum ntawm cov poj niam nrog txo lub cev tsis kam thaum kho nrog tshuaj tua kab mob los yog lwm yam tshuaj uas cuam tshuam nrog microflora qhov chaw mos.
Tsuas tshuaj thiab tswj hwm
Sab hauv, cov tshuaj yuav tsum noj nrog zaub mov 1 zaug hauv ib hnub. Cov koob tshuaj txhua hnub rau cov neeg laus thiab cov menyuam yaus lub cev hnyav dua 30 kg yog 200-400 mg, rau cov menyuam yaus hnyav dua 30 kg - 4-8 mg / kg.
Lub sijhawm kho mob, nyob ntawm qhov ntsuas:
- Dermatomycosis - 2-8 lub lim tiam,
- Onychomycosis thiab mob candidiasis - txog thaum ua tiav rov qab (feem ntau nws yuav siv sijhawm li 4 txog 6 lub lim tiam),
- Cov kab mob voos ntawm qhov ncauj kab noj hniav, lub plab zom mov thiab lub kaw lus genitourinary - kom txog thaum rov ua tiav (4-6 lub lis piam),
- Systemic mycoses - ntau lub hlis,
- Kev tiv thaiv cov kab mob fungal - lub sijhawm tswj xyuas nyob ntawm seb hom thiab chav kawm ntawm tus kabmob pib.
Nrog mycosis ntawm lub qhov muag, 1 ntsiav tshuaj hauv ib hnub yog daim ntawv kho mob. Hauv cov txhab txhab mob sib cuag rau lub ntsej muag ntawm lub qhov muag, qhov emulsion raws ketoconazole tseem siv. Rau qhov no, tam sim ntawd ua ntej siv, 1 ntsiav tshuaj yog diluted nyob rau hauv 5 ml ntawm 4,5% kev daws ntawm boric acid, cov txiaj ntsig tau muab faus 5-6 zaug hauv ib hnub hauv hnab looj ntsej muag.
Ketoconazole suppositories tau txhaj ntxaum mus rau hauv qhov chaw mos nyob rau hauv txoj hauj lwm supine, 1 suppository ib hnub ib zaug rau 3-5 hnub, nrog mob candidiasis - 10 hnub.
Cov tshuaj nplaum tau thov ib hnub ib zaug rau cov tawv nqaij ua haujlwm, ua kom ntev li 2 cm ntawm thaj chaw noj qab haus huv. Tom qab cov tsos mob ploj, kev kho yog pom zoo kom txuas ntxiv rau ob peb hnub ntxiv. Qhov nruab nrab ntawm kev kho mob ntev:
- Candidamycosis thiab pwm mycosis - 2-3 lub lis piam,
- Dermatophytosis - 2-6 lub lis piam,
- Seborrheic dermatitis - 2-4 lub lis piam (nrog rau cov kabmob no, ntau zaus ntawm kev thov tuaj yeem raug nce rau 2 tauj ib hnub).
Ketoconazole zawv plaub hau yog thov rau thaj chaw muaj kev cuam tshuam, sab laug rau 3-5 feeb, thiab tom qab ntawd ntxuav tawm nrog dej:
- Mould mycoses: kev kho mob - 1 zaug hauv ib hnub rau 5 hnub, kev tiv thaiv - 1 zaug hauv ib hnub rau 3 hnub,
- Seborrheic dermatitis: kho - 2 zaug ib vas thiv rau 2-4 lub lim tiam, kev tiv thaiv - 1 zaug hauv ib lub lis piam txhua 1-2 lub lis piam,
- Dandruff: kev kho mob - 1 zaug txhua 3-4 hnub rau 8 lub lim tiam, kev tiv thaiv - raws li xav tau ntawm kev tswj hwm hauv chaw soj ntsuam.
Muaj nuj nqi thiab cov nyhuv
Tsis zoo li nws cov neeg sib tw, cov khoom muaj ob nyhuv:
- Ua ntej, qhov no yog qhov ua tau zoo ntawm cov kev ua haujlwm ncaj qha, cov uas yog kev tiv thaiv thiab pov tseg cov kab mob ntawm cov plhaws, ua tsaug rau 2% ntawm ketoconazole, uas yog ib feem ntawm cov tsuaj zawv plaub hau.
- Thib ob, qhov no cuam tshuam rau thaj chaw ntawm daim tawv nqaij los ntawm kev tshem tawm foci ntawm o. Tsis tas li ntawd xwb, cov khoom no muaj cov tshuaj tua kabmob thiab tshuaj tua kabmob, uas muaj kev cuam tshuam zoo sai ntawm kev kho kom zoo.
Tsuaj zawv plaub hau muaj ntau txoj haujlwm kho:
- txhim kho pom tshwm sim hauv tawv nqaij tom qab siv ketoconazole,
- fungus txo ntawm lub taub hau,
- kev tshem tawm ntawm faib cov hlwb thiab "nplai", tiv thaiv lawv cov tsos,
- kev tiv thaiv ntawm kev zais ntawm sebum, roj plaub hau.
Cov lus qhia kho kom raug
Yog tias koj xav txhim kho cov mob ntawm koj cov plaub hau, yuav tsum muaj kev tshwj xeeb rau cov tshuaj zawv plaub hau uas koj siv.
Daim duab txaus ntshai - nyob rau 97% ntawm cov muaj npe zoo ntawm tshuaj zawv plaub hau yog cov tshuaj uas lom peb lub cev. Cov khoom tseem ceeb vim tias txhua yam teeb meem hauv cov ntawv sau npe yog sodium lauryl sulfate, sodium laureth sulfate, coco sulfate. Cov tshuaj no rhuav tshem cov qauv ntawm curls, plaub hau ua nkig, poob elasticity thiab lub zog, xim yuav ploj mus. Tab sis qhov tsis zoo tshaj plaws yog tias lub pob muck no nkag mus rau hauv lub siab, lub siab, lub ntsws, kev sib sau hauv cov plab hnyuv siab raum thiab tuaj yeem ua rau mob qog nqaij hlav.
Peb qhia koj kom tsis kam lees siv cov nyiaj nyob hauv cov tshuaj no. Tsis ntev los no, cov kws tshaj lij los ntawm peb lub chaw haujlwm sau cia ua ib qho kev tsom xam ntawm cov tshuaj zawv plaub hau uas tsis muaj tshuaj, qhov twg nyiaj los ntawm Mulsan Cosmetic tau ua thawj qhov chaw. Cov tuam txhab tsim khoom ntawm cov tshuaj pleev ib ce tag nrho. Txhua yam khoom tsim yog ua los ntawm kev tswjhwm nruj thiab daim ntawv pov thawj.
Peb pom zoo kom mus saib hauv online khw khw mulsan.ru. Yog tias koj tsis ntseeg qhov natural ntawm koj cov tshuaj pleev ib ce, xyuas lub sijhawm tas sij hawm, nws yuav tsum tsis pub ntau tshaj ib xyoos ntawm kev khaws cia.
Cov hau kev thov qauv
Feem ntau, cov ntsiab lus ntawm ketoconazole hauv cov tsuaj zawv plaub hau yog 1-2 feem pua, yog li nws tuaj yeem siv thaum pib mus txog thaum kawg 2 zaug ib lub lim tiam, thiab thaum cov nyhuv tshwm sim, thiab cov zwj ceeb ntawm lub hau hloov kho, nws yuav txaus txawm tias ib zaug rau 1-2 hlis.
Tsuaj zawv plaub hau tau pom zoo rau cov neeg muaj 12 xyoos rov hauv uas muaj teeb meem rau cov kab mob fungal, nrog rau dermatophytosis thiab candidiasis. Ua ntej yuav zawv plaub hau, koj yuav tsum sab laj nrog trichologist thiab dermatologist.
Cov lus qhia rau kev siv: siv me ntsis tshuaj zawv plaub hau rau cov plaub hau kom noo, txhuam kom huv rau cov hauv paus hniav thiab tawv nqaij nrog cov plaub hau zaws, thiab tom qab ntawd muab faib rau thoob ntev tag nrho. Sau ntawv cia nyob rau 5 feeb. Yaug kom huv nrog dej sov kom cov tshuaj tsis nyob hauv taub hau. Haum rau ib hom plaub haurau txiv neej thiab poj niam.
Lub chav kawm ntawm kev siv yog tsim rau 2-4 lub lis piam. Nyob rau tib lub sijhawm, tshuaj tua kab mob nrog ketoconazole yuav tsum tau siv, hloov lawv nrog tshuaj zawv plaub hau ib txwm siv.
Cov tshuaj ua ke ntawm cov tsuaj zawv plaub hau
Feem ntau, tsuaj zawv plaub hau nrog ketoconazole yuav suav nrog cov tshuaj xws li:
- Cyclopirox, 1% (Sebiprox). “Seborrheic dermatitis” tiv thaiv tus kab mob, muaj tshwm sim tom qab siv thawj zaug.
- Selenium sulfide. Nws muaj feem xyuam rau kev ua kom qeeb ntawm cell faib, tua thiab tawm tsam tawm tsam fungus.
- Zinc pyrithione. Nws tshem tawm cov khaus khaus, hlawv, ua qeeb qeeb thiab tshem tawm qhov kev ua ntawm lub cev fungus, nkag mus rau hauv cov nqaij sib sib zog nqus ntawm cov tawv taub hau. Nws yog ib feem ntawm Taub Hau thiab xwb pwg thiab lwm cov tshuaj zawv plaub hau kom nrov.
- Kev kho mob tar. Nws kis tau zoo nrog tawv nqaij ua paug thiab tev tawv nqaij, tab sis tsis tshua muaj txiaj ntsig hauv kev tua cov pwm. Muaj nyob hauv cov tshuaj zawv plaub hau Friderm Tar, T / Gel Neutrogena, Cebuto.
Muaj kev phiv ntau
Txawm hais tias tag nrho nws cov txiaj ntsig, ketocanazole muaj ntau yam kev mob tshwm sim uas tuaj yeem cuam tshuam cov mob ntawm tus neeg siv. Qhov tseeb yog tias tib neeg lub cev yog tus kheej tsim, yog li muaj qhov ntxim nyiam ntawm kev tiv thaiv kev tawm tsam rau qee yam ntawm cov tshuaj. Feem ntau, cov tshuaj zawv plaub hau tsis ua rau ua rau ua rau khaus lossis lwm yam mob.
Ua ntej siv cov tsuaj zawv plaub hau, nws pom zoo kom sab laj nrog tus kws kho mob. Thaum muaj teeb meem hauv qab no, tsis txhob siv tshuaj koj tus kheej:
- Muaj qee kis, kev siv ketocanazole ua rau mob tawv nqaij xws li khaus, ua xua hauv zos ntawm daim tawv nqaij, nrog rau qhov tshwm sim ntawm cov tawv nqaij sib chwv.
- Tsis tshua muaj neeg siv, qhov tshwm sim tsis zoo yog tshwm sim hauv kev ua tsis zoo ntawm cov qog sebaceous.
- Cov tsos mob uas tsis pom zoo tshaj plaws ntawm kev tsis lees yuav yog kev hloov pauv ntawm cov plaub hau xim. Tej zaum yuav tshwm sim hauv cov tswv ntawm grey los yog dyed plaub hau.
Cov tshuaj no tsis yog tsim rau kev siv lub qhov ncauj. Yog tias qhov no tau tshwm sim ntawm random, tom qab ntawd muaj qhov ua tau ntawm qhov tshwm sim ntawm cov tsos mob hauv qab no:
- Sib cuag nrog cov tshuaj ua rau lub zog hlawv, txhawm rau tshem tawm uas nws yog qhov yuav tsum tau yaug qhov txhab nrog dej.
- Yog tias tsuaj zawv plaub hau los rau hauv lub qhov ncauj thiab mam li nkag mus rau txoj hnyuv, kem plab tuaj, nrog ntuav lossis raws plab.
Tsis tas yuav tsum sim ua kom tshem tawm cov txheej txheem no rau koj tus kheej, txij li kev kho mob nrog cov tshuaj tsis raug cai lossis cov neeg kho tsis tau txaus ntseeg tuaj yeem hloov pauv mus rau theem nyuaj dua. Txoj hauv kev zoo tshaj plaws ntawm qhov xwm txheej no yog kom tsis txhob siv cov khoom thiab tam sim ntawd mus ntsib kws kho mob tawv nqaij.
